Method Development

Our scientists take a practical approach to analytical method development, creating new methods and transferring technology as needed to quality control labs.

For HPLC methods, we use affordable, readily available solvents and columns (unless specialty items are necessary for your project). Our detection mode expertise includes:

            Evaporative light scattering detector (ELSD)
Mass Spectrophotometer
Florescence
Diode array
Multiwavelength

Our scientists have experience with the following analytical methods:

HPLC Methods
Reverse Phase
Size Exclusion
Gel Filtration
Ion Exchange
Hydrophobic Interaction

Peptide Maps

Plate Reader
A280
Total content
Elisa
Enzymatic assay

Nanodrop for protein concentration
High concentration analysis

Modulated Densitometry Scanning Calorimeter
Thermal profiles

Fluorimeter
Tagg and Tm determination

Dynamic Light Scattering
Particle size and zeta potential

Capillary Electrophoresis
Reduced and non-Reduced SDS capillary, glycan analysis
cIEF

SDS-Page
Reduced and Non-Reduced SDS-Page

Densitometer Gel Scanning 

Isoelectric Focusing

Moisture Analysis
Karl Fisher Method

Flowcam
Total particle count

Viscosizer
Viscosity and particle size

Osmolality
In-use stability studies with infusion pumps and syringes

CuriRx can also perform routine analyses, from simple melting point determinations or UV/VIS scans to non-GMP Stability Testing.